The safety and efficacy of TIL cell therapy are under investigation and have not been established.
There are no guarantees that TIL cell therapies will receive US FDA approval for the uses being investigated.

What Is the Investigational TIL Cell Therapy Process?

In investigational TIL cell therapy, a small piece of an individual’s tumor is used to generate billions of rejuvenated TIL in a laboratory1

Tumor tissue procurement

A small portion of the tumor is surgically collected and sent to a specialized laboratory.

GMP manufacturing

The patient’s TIL are separated from other cells in the tumor.

Amplification and reinvigoration

The TIL are rejuvenated and multiplied into the billions.

Infusion of billions of reinvigorated TIL

The multiplied and reenergized TIL are administered back to the patient during a hospital stay.

FDA=Food and Drug Administration; GMP=good manufacturing practice; TIL=tumor infiltrating lymphocytes.

Reference: 1. Wardell S, Lienlaf-Moreno M, Blaskovich M, et al. Iovance Gen 2 TIL manufacturing process produces drug products that exhibit favorable quality attributes for adoptive cell transfer across 5 solid tumor indications. Poster P226 presented at: SITC Annual Meeting; November 6-10, 2019; National Harbor, MD.

Contact us

Iovance Biotherapeutics 825 Industrial Road, Suite 400
San Carlos, CA 94070

Phone: 650-260-7120

Register for updates from Iovance
Register for updates